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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-10
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filingDate 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113004266-B
titleOfInvention A kind of fluorescent probe based on benzothiazolol-hemicyanine system and its preparation method and application
abstract The invention relates to a fluorescent probe based on a benzothiazolephenol-hemicyanine system, a preparation method and application thereof, and belongs to the technical field of fluorescent probe detection. The invention provides a fluorescent probe based on a benzothiazolephenol-hemocyanine system, the fluorescent probe has strong sensitivity and selectivity, fast response speed, and wide linear detection range (pH 3.0-10.0) As well as a suitable pK a value (7.92), the probe can be used for semi-quantification of the pH of the analyte under naked eye colorimetry, and can be used for high-throughput detection of large samples; and it has good biocompatibility, cell It has low toxicity, can also be used for real-time monitoring of mitochondrial pH value, and has potential and broad application prospects in various pathological processes caused by abnormal mitochondrial pH; the invention also provides a preparation method of the fluorescent probe, which has mild reaction conditions , convenient post-processing, high yield, low cost and so on.
priorityDate 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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