http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113004137-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 |
| filingDate | 2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113004137-B |
| titleOfInvention | Blood sugar and blood fat reducing polyketone compound and preparation method and application thereof |
| abstract | The invention relates to a streptomyces sourced from soil in Antarctic Zhongshan stand Streptomyces A preparation method for producing polyketone compounds by sp.HDN15176 (preservation number: CGMCC No. 17648), and simultaneously relates to the application of the compounds in reducing blood sugar and blood fat, the structural formula is as follows: (ii) a It can be produced by Streptomyces Streptomyces Obtaining a fermentation product containing the compound by sp.HDN15176 fermentation culture, and then separating and purifying by methods such as VLC normal phase column chromatography separation, C-18ODS reversed phase column chromatography separation, semi-preparative HPLC and the like. The invention aims to provide a novel compound with a novel structure and protein tyrosine phosphatase 1B inhibitory activity from secondary metabolites derived from fungi, and the compound can be used as a novel hypoglycemic and hypolipidemic agent for treating hyperglycemia and hyperlipidemia. |
| priorityDate | 2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.