http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112999370-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bbdac88c2bd304b523b4ea0ea461bea |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 |
| filingDate | 2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c4c2bcf2032d9596ff09d7cdc626482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_605ed57e14bc403bf63e057376d9f460 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_677ff0fa2358ba6e11ac05a5094cc553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d411a98f88b3866dc7f78bb44cac380 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad805853048f24ce8f13c761d1cfe7ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8beaad82d4e15ae1df2439dc788a67bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47efbc102c0dc6a8c223ba75f10b1526 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28ebd1084bf33d508bd0d7ccc8dae61d |
| publicationDate | 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112999370-A |
| titleOfInvention | A tumor molecular probe targeting cervical cancer and its application |
| abstract | The invention discloses a tumor molecular probe targeting cervical cancer and its application. The present invention provides a method for preparing a tumor molecular probe, comprising the steps of: carrying out99mTc labeling on a Pep-1 polypeptide modified with MAG 3 to obtain the tumor molecular probe. The present invention synthesizes and prepares a 99m Tc-MAG 3 -Pep-1 probe that meets the clinical transformation standard, and it has strong in vitro stability after testing. In addition, the present invention also explores the effect of the probe on subcutaneous tumor-bearing (cervical cancer). The imaging application value of the mouse model can better reveal the biological properties of the molecular probe and its potential application prospects. The present invention focuses on three aspects of nuclear medicine, basic medicine and clinical transformation, and prepares a 99m Tc-MAG 3 -Pep-1 molecular probe with high labeling rate, high specific radioactivity and high radiochemical purity, which is used for further animal research. Experimental research and clinical transformation have laid a solid foundation. |
| priorityDate | 2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.