abstract |
The present invention relates to a compound capable of inhibiting the binding of Yes associated protein (Yes associated protein, YAP)-transcriptional enhancer associate domain (TEAD), its prodrug, its hydrate, its solvate or its pharmacy Acceptable salts and compositions containing them as active ingredients, the compounds of the present invention can act as inhibitors capable of directly inhibiting YAP-TEAD binding in the Hippo pathway, which plays a central role in the development of cancer. |