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filingDate 2021-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112980043-B
titleOfInvention Homogeneous core-shell structure porous chitosan microsphere and preparation method and application thereof
abstract The invention discloses a porous chitosan microsphere with a homogeneous core-shell structure, wherein the porous chitosan microsphere is of a core-shell structure, both a shell layer and a spherical core are made of chitosan, the shell layer is of a compact structure, the spherical core is of a porous structure with staggered lamellar shapes, and the length of a lamellar hole is 50-100 mu m; the diameter of the porous chitosan microsphere is 100-500 mu m, and the thickness of the shell layer is 10-40 mu m. The invention also discloses a preparation method of the porous chitosan microsphere with the homogeneous core-shell structure and application of the porous chitosan microsphere in three-dimensional soft acoustic metamaterial, medicine carrying and medicine slow release. The preparation method synthesizes the core-shell structure in situ, the existence of the shell structure can prevent or slow down the material transmission of the porous microspheres and the environmental matrix, and the effective working time of the microspheres is prolonged.
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