http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112979968-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-02 |
| filingDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112979968-B |
| titleOfInvention | Cartilage targeting zwitterionic polymer and preparation method and application thereof |
| abstract | The invention belongs to the field of high molecular functional materials, and particularly relates to a cartilage targeting zwitterionic polymer and a preparation method and application thereof, wherein a methacryloyl chloride modified N-hydroxysuccinimide monomer is synthesized for realizing efficient chemical grafting of cartilage targeting peptide; secondly, the cartilage targeting zwitterionic polymer is obtained through random copolymerization or RAFT polymerization. The polymer can be targeted to the cartilage surface, enhances the lubricating property of the articular cartilage, avoids abrasion in the movement process, and in addition, the antifouling property provided by the zwitterion unit can resist the damage of degrading enzymes to the cartilage matrix, thereby realizing hose protection. The cartilage targeting zwitterionic polymer has wide application prospect in bone tissue engineering. |
| priorityDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.