http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112979942-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2377-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L77-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate | 2021-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112979942-B |
| titleOfInvention | Polyamino acid block polymer with functionalized side group, preparation method thereof and response type reversible adhesion injectable hydrogel |
| abstract | The invention provides a polyamino acid block polymer with functionalized side groups, which comprises an A block and a B block. Compared with the prior art, the invention takes the A block as the hydrophilic continuous segment and the B block as the hydrophilic and hydrophobic adjustable segment, and the two blocks have different polymerization degrees, so that block polymers with different molecular weights can be obtained, and temperature and pH sensitive hydrogel with different phase transition temperatures can be formed; meanwhile, the block shown in the formula (III-C) in the block B can be protonated and deprotonated to realize hydrophilic-hydrophobic property conversion, so that the reversible conversion of sol-gel is realized; moreover, the type and the number of the side groups can be changed by controlling the composition of the B block, thereby being beneficial to further modification and application of materials; moreover, the polyamino acid block polymer provided by the invention obviously enhances the adhesion functions of PMMA, stainless steel, cells and the like, expands the application range of the temperature-sensitive hydrogel and is beneficial to the application of the temperature-sensitive hydrogel in the aspect of biomedicine. |
| priorityDate | 2021-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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