http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112979566-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6915bbade42d3f45d2267b2661941c5a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-08 |
| filingDate | 2021-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0b15d5cfb4506e057a929f4083e09b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_336212c3ff654a3e07a2da7bb0e09045 |
| publicationDate | 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112979566-A |
| titleOfInvention | Preparation method of deferasirox |
| abstract | The invention discloses a preparation method of deferasirox, which comprises the following steps: 1) dissolving the crude product of deferasirox in tetrahydrofuran or methyltetrahydrofuran, decoloring by using decoloring equipment, adding an organic solvent, and washing an organic phase by using a weak alkaline aqueous solution; 2) extracting organic phase, adjusting pH of the extractive solution to 3, and filtering; 3) pulping the solid obtained by filtering, performing reflux pulping, cooling and filtering to obtain a refined deferasirox product, wherein the organic solvent is selected from isopropyl ether, dichloromethane, n-hexane and petroleum ether; the reagent used for extracting the organic phase is sodium hydroxide aqueous solution. |
| priorityDate | 2021-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.