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filingDate 2021-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112972749-B
titleOfInvention High-efficiency hemostatic material based on chitosan fiber and preparation method thereof
abstract The invention provides a chitosan fiber-based high-efficiency hemostatic material and a preparation method thereof. The invention firstly carries out spinning on chitosan to obtain a chitosan fiber substrate, and then simultaneously grafts carboxyl and catechol structures on the chitosan fiber substrate. The hemostatic material can rapidly absorb water in blood to swell, thereby remarkably improving the hemostasis rate. The introduction of carboxyl makes it have super strong liquid absorbing capacity, so that the blood platelet in the blood of bleeding part can be quickly adhered and aggregated to form thrombus, and the hydroxyl on the catechol group can be complexed with the iron ion in the blood erythrocyte, so that the erythrocyte is aggregated to play the role of stabilizing blood clot, and finally the effect of quickly stopping bleeding is achieved. The high-efficiency hemostatic material provided by the invention is particularly suitable for the condition of massive hemorrhage.
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