http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112972685-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112972685-B |
titleOfInvention | Application of substances that increase the activity and/or expression of liver SIRT5 protein in the treatment of acute myocardial infarction |
abstract | The invention discloses the application of substances that increase the activity and/or expression of liver SIRT5 protein in the treatment of acute myocardial infarction. Experiments showed that compared with C57BL/6 mice, the myocardial infarction area and myocardial fibrosis area of C57BL/6 mice with liver-specific overexpression of SIRT5 protein were significantly reduced, and the cardiac function was improved to a certain extent. It can be seen that substances that increase the activity and/or expression of SIRT5 protein in the liver can reduce the size of myocardial infarction, reduce the area of myocardial fibrosis and improve cardiac function, and further prevent and/or treat acute myocardial infarction. The invention has important application value. |
priorityDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.