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filingDate 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112972685-B
titleOfInvention Application of substances that increase the activity and/or expression of liver SIRT5 protein in the treatment of acute myocardial infarction
abstract The invention discloses the application of substances that increase the activity and/or expression of liver SIRT5 protein in the treatment of acute myocardial infarction. Experiments showed that compared with C57BL/6 mice, the myocardial infarction area and myocardial fibrosis area of C57BL/6 mice with liver-specific overexpression of SIRT5 protein were significantly reduced, and the cardiac function was improved to a certain extent. It can be seen that substances that increase the activity and/or expression of SIRT5 protein in the liver can reduce the size of myocardial infarction, reduce the area of myocardial fibrosis and improve cardiac function, and further prevent and/or treat acute myocardial infarction. The invention has important application value.
priorityDate 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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