http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112972679-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
filingDate 2021-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112972679-B
titleOfInvention A polypeptide-coupled boron carrier and its preparation method and pharmaceutical preparation
abstract The invention discloses a boron-carrying agent, a preparation method and a pharmaceutical preparation thereof, wherein the boron-carrying agent comprises compound 1 N-4-carboxyphenylboronic acid amide-threo-benzene-phen-phenol-gan-gan-silk-essence- Gan-Lai-Jin-Aspart-Aspart-Benzene-Lay-Sue-Valu-Valu-Tyro-Cysteine, the molecular formula is C 114 H 158 BN 30 O 35 S 1 , the molecular weight is 2552.4, and it also includes Compound 2 N-4-Carboxyphenylboronic acid amide-es-lys-lys-lys-sing-sing-glutamyl-essence-arginine, and/or compound 3N-4-carboxyphenylboronic acid amide-methyl-propane-silk- M-Su-Gan-Gan-Glutyl-Glutyl-M-Glycine. The compound of the present invention can be used as a targeted boron neutron capture therapeutic drug for the treatment of brain glioma and head and neck tumors.
priorityDate 2021-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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