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filingDate 2021-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba9633e3c63f3512d4397678c68f3a73
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publicationDate 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112972468-A
titleOfInvention Use of alkaloid compound Hip in the preparation of products for preventing and/or treating heart damage
abstract The invention discloses the use of the alkaloid compound Hip in the preparation of products for preventing and/or treating cardiac injury. The activity research of the alkaloid compound Hip has been carried out to verify that the alkaloid compound Hip provided by the invention can inhibit the myocardial toxicity induced by the effect of Apoptosis, by down-regulating the expression levels of p-JNK and/or Cleaved-Caspase-3 to inhibit the apoptosis of cardiomyocytes induced by anthracycline DOX, thereby relieving cardiotoxicity and preventing and/or treating cardiotoxicity The effect can be used to prepare a drug for preventing and/or treating myocardial injury-related diseases.
priorityDate 2021-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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