Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a19efb85153bd83f1c87e82dc0e9b9da |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-185 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate |
2021-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba9633e3c63f3512d4397678c68f3a73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd8bcc61d3d4dcd6b23a821dd1fd0de5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c65552c4d6928bc3d88f67165cfcc30 |
publicationDate |
2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-112972468-A |
titleOfInvention |
Use of alkaloid compound Hip in the preparation of products for preventing and/or treating heart damage |
abstract |
The invention discloses the use of the alkaloid compound Hip in the preparation of products for preventing and/or treating cardiac injury. The activity research of the alkaloid compound Hip has been carried out to verify that the alkaloid compound Hip provided by the invention can inhibit the myocardial toxicity induced by the effect of Apoptosis, by down-regulating the expression levels of p-JNK and/or Cleaved-Caspase-3 to inhibit the apoptosis of cardiomyocytes induced by anthracycline DOX, thereby relieving cardiotoxicity and preventing and/or treating cardiotoxicity The effect can be used to prepare a drug for preventing and/or treating myocardial injury-related diseases. |
priorityDate |
2021-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |