http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112961805-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y306-04012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y599-01002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-42 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
filingDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112961805-B |
titleOfInvention | Salmonella typhimurium with quinolone drug resistance genes gyrA and parE mutated simultaneously and application thereof |
abstract | The invention relates to the technical field of drug-resistant strains, in particular to salmonella typhimurium with quinolone drug-resistant genes gyrA and parE mutated simultaneously and application thereof. The salmonella typhimurium simultaneously carries two quinolone drug resistance mutation sites, wherein the two quinolone drug resistance mutation sites are respectively as follows: the 83 th serine of the encoded product of the gyrA gene is mutated into phenylalanine; the 333 rd threonine of the product encoded by the parE gene was mutated to isoleucine. These mutation sites cause salmonella to exhibit drug resistance or intermediate resistance to quinolone drugs. Therefore, the salmonella provided by the invention can be used as a model material for screening novel antibacterial drugs, and has a good application prospect. |
priorityDate | 2020-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.