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filingDate 2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112961393-B
titleOfInvention Anticoagulant biomaterial and its use in blood collection device
abstract The present invention provides anticoagulation biomaterials and their use in blood collection devices, and relates to the field of medical biomaterials. The biomaterials include a substrate, an anticoagulation layer, and an adhesion layer and Hydrophilic layer; its preparation method comprises: carrying out dopamine modification and polyallylamine grafting reaction on the substrate to obtain ammonia-rich pretreatment of ammonia-rich substrate; In the solution, the hydrophilization treatment of the hydrophilic material obtained by grafting reaction with hyaluronic acid; the alternate deposition of polycation and polyanion electrolyte on the surface of the hydrophilic material to obtain the self-assembly treatment of the self-assembled material; and the The self-assembled material is thermally cured. The anticoagulant biological material provided by the invention has high interlayer bonding stability, high retention rate of the hydrophilic layer and the anticoagulation layer, good durability and stability of the anticoagulation effect, and has excellent liquid absorption ability and self-absorption. Effect; The material is used to prepare suction blood vessels or storage blood vessels or blood transfusion catheters of blood collection devices.
priorityDate 2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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