http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112961173-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate | 2021-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112961173-B |
| titleOfInvention | Prostate specific membrane antigen targeted molecular probe, preparation method and application thereof |
| abstract | The invention relates to the field of medicines, in particular to a prostate specific membrane antigen targeted molecular probe, a preparation method and application thereof. The present invention provides a prostate specific membrane antigen targeting molecular probe [ 2 ] 18 F]GLNTGT has good stability in vitro, shows good biocompatibility in prostate cancer cells with different PSMA expressions, and determines the tracer [ 2 ] for the specific targeting of PSMA 18 F]GLNTGT has high tumor cell uptake rate and high binding affinity to PSMA. [ 18 F]Mouse control tracer [ GLNTGT ] of a group 18 F]AlF‑NOTA‑RGD 2 Has higher target cost ratio. Despite the tracer [ 2 ] 18 F]GLNTGT has some limitations in cell and in vivo CT signal detection experiments, but still provides reference for the development of PET/CT tracers. |
| priorityDate | 2021-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.