http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112957521-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-626 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0066 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L26-00 |
| filingDate | 2021-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112957521-B |
| titleOfInvention | A kind of preparation method of artemisinin liposome-loaded alginate-silk fibroin composite hydrogel |
| abstract | The invention relates to the field of biomedical materials, and the invention discloses a preparation method of an artemisinin-loaded liposome alginate-silk fibroin composite hydrogel. In the invention, the artemisinin injection method is used to inject artemisinin in an appropriate proportion. Vegan drugs and other lipids were dissolved in ethanol, injected and evaporated to prepare liposomes loaded with artemisinin drugs; degummed with sodium carbonate solution, and a ternary system of CaCl 2 ‑ethanol‑H 2 O was selected to stir and dissolve silk fibroin protein, centrifugal dialysis, freeze-drying to prepare silk fibroin; sodium alginate solution is prepared, then drug-loaded liposome, silk fibroin, sodium alginate are formed into a mixture, and hydrogel is prepared by centrifugal ultrasonic wave, which has excellent drug control. The biocompatibility of the hydrogel prepared by compounding sodium alginate and silk fibroin is also very good. Mechanical properties of gels. |
| priorityDate | 2021-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.