http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112957341-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5068 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2021-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112957341-B |
titleOfInvention | Phillyrin loading and drug delivery system for MHS cell-derived exosomes and application thereof |
abstract | The invention relates to the technical field of biological medicine, in particular to a forsythin loading and drug delivery system based on MHS cell-derived exosomes and application thereof. The drug delivery system is prepared by mixing MHS cell-derived exosomes and a phillyrin solution, and then performing incubation, ice bath ultrasound, constant-temperature culture recovery, centrifugation, washing and resuspension, centrifugation and resuspension precipitation; in the mixed solution, the concentration of the phillyrin is 400-; the concentration of MHS cell-derived exosomes was 400-410. mu.g/mL based on the amount of protein. The Phil-Exos prepared by the invention is well taken up by the A549 cells, has higher inhibition effect on the migration of the A549 cells, and obviously improves the anti-tumor cell migration capability of the Phil. |
priorityDate | 2021-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.