http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112957331-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-436 |
| filingDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112957331-B |
| titleOfInvention | Nano-assembly of co-loaded rapamycin and curcumin and preparation method and use thereof |
| abstract | The invention provides a nano-assembly co-loaded with rapamycin and curcumin and a preparation method and application thereof. In the nano-assembly, the mass ratio of rapamycin and curcumin is (3.0-4.0):1. Compared with free rapamycin and free curcumin, the above nanoassemblies can effectively regulate the transformation of macrophages from inflammatory M1 state to anti-inflammatory M2 state, improve pulmonary inflammation caused by acute lung injury, and reduce acute lung injury. The total protein content in the lungs of mice has a synergistic effect on the treatment of acute lung injury, and the invention provides a new choice for preparing a drug for the treatment of acute lung injury. |
| priorityDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.