abstract |
The present disclosure relates to a novel small molecule CD73 inhibitor, its preparation method and its application in medicine. Specifically, the present disclosure relates to a small molecule CD73 inhibitor represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, and its use as a therapeutic agent, especially in the preparation for the treatment of CD73 mediators. Use in the medicament of the induced diseases and disorders, wherein each substituent of the general formula (I) is as defined in the specification. |