http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112946099-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2021-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112946099-B |
| titleOfInvention | A method for detecting related substances in amino acid glucose injection |
| abstract | The invention relates to the technical field of drug analysis and detection, and specifically discloses a method for detecting related substances in amino acid glucose injection. The present invention adopts high-performance liquid chromatography for detection, and the chromatographic conditions are: chromatographic column: octadecylsilane bonded silica gel column; detection wavelength 205-215nm, mobile phase A is phosphoric acid aqueous solution of pH2.8-3.2, and mobile phase B For acetonitrile, gradient elution. The detection method provided by the present invention can effectively separate various amino acids from multiple known impurities and unknown impurities, and the method provided by the present invention has been verified by methodologies such as specificity and sensitivity, and it is found that the method of the present invention is sensitive and accurate , the reproducibility is good, and the quantitative detection of more impurities in the amino acid glucose injection can be realized with a simpler method, which provides a reliable method for the preparation process of the amino acid glucose injection and the quality control of the product, and Conducive to improving the drug safety of patients. |
| priorityDate | 2021-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.