http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112940002-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-824 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6571 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2461 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6571 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-24 |
| filingDate | 2021-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112940002-B |
| titleOfInvention | A kind of method for synthesizing eight-membered bridged ring compound by palladium-catalyzed asymmetric cycloaddition reaction |
| abstract | The invention provides a method for synthesizing an eight-membered bridged ring compound through a palladium-catalyzed asymmetric cycloaddition reaction, comprising the following steps: in an organic solvent, catalyzed by a palladium catalytic system and in the presence of additives, γ-methylene-δ -Valerolactone compound I and benzo[C]isoxazole compound II undergo a [4+4] cycloaddition reaction to obtain an eight-membered bridged ring compound III; the palladium catalyst system is composed of a palladium catalyst and a chiral ligand . The method of the invention can generate an eight-membered bridged ring compound with high stereoselectivity and regioselectivity, and can perform high-efficiency asymmetric synthesis of the eight-membered ring compound; The method of the eight-membered ring compound has the advantages of convenient operation, wide application range of substrates, cheap and readily available reaction raw materials, and the like. |
| priorityDate | 2021-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.