http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112939864-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 |
| filingDate | 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112939864-B |
| titleOfInvention | Spiro [ benzo [ c ] aza-1, 1' -cyclohexyl ] -3-ones |
| abstract | The invention belongs to the technical field of medicines, and relates to a medicineA compound with a specific chemical structure and anti-tumor activity, in particular to 4, 5-dihydrospiro [ benzo [ c ]]Aza-1, 1' -cyclohexyl]-3(2H) -ketone compound and preparation method and application thereof. The structural general formula of the compound is as follows: wherein: a R group on the benzene ring is substituted by 2-position, 3-position or 4-position mono-substituted fluorine atom, methyl, chlorine atom, methoxyl, bromine atom or hydrogen atom. Pharmacological research shows that the compound provided by the invention has certain inhibitory activity on human colon cancer HCT-116 cells, can be used for preparing antitumor drugs, and opens up a new way for the deep research and development of future tumor drugs. The preparation method provided by the invention is simple and feasible, has high yield and is easy for large-scale production. |
| priorityDate | 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.