http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112939849-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-78 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2019-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112939849-B |
| titleOfInvention | (S, S) -2, 8-diazabicyclo [4.3.0] nonane intermediate and preparation method and application thereof |
| abstract | The invention discloses a (S, S) -2, 8-diazabicyclo [4.3.0] nonane intermediate and a preparation method and application thereof, wherein a new compound, namely compounds II to V, is used as a key intermediate to develop a new route for synthesizing (S, S) -2, 8-diazabicyclo [4.3.0] nonane, and the route takes dialkoxy acetate as an initial raw material and sequentially carries out claisen condensation, substitution reaction, intramolecular dehydration cyclization, catalytic hydrogenation reduction, chiral resolution, dissociation, hydrolysis, intramolecular dehydration cyclization and catalytic hydrogenation to obtain the (S, S) -2, 8-diazabicyclo [4.3.0] nonane. The preparation method disclosed by the invention is simple in preparation process, high in total reaction yield, good in product quality, green and environment-friendly in process route, and has good industrial application prospect. |
| priorityDate | 2019-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.