http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112939737-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-28 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C35-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-86 |
| filingDate | 2021-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112939737-B |
| titleOfInvention | A compound extracted from burdock leaves and capable of protecting alcohol-induced liver injury and its preparation method and application |
| abstract | The invention relates to a compound with protection against alcoholic liver injury extracted from burdock leaves and a preparation method and application thereof, which can effectively solve the problem of preparing compounds with protection against alcoholic liver injury from burdock leaves, and develop new uses of burdock leaves for medicinal value The problem, the method is, burdock leaves are soaked in water, filtered, concentrated, sequentially extracted with ethyl acetate, the ethyl acetate extract is concentrated under reduced pressure, subjected to silica gel column chromatography, eluted with dichloromethane-methanol gradient, and the solvent is recovered under reduced pressure , and then carry out MCI column chromatography, gradient elution with methanol aqueous solution, combined eluents, drying, and recrystallization in methanol to obtain compounds with lipid-lowering protection and alcohol-induced liver injury extracted from burdock leaves. The preparation method of the present invention It is easy to operate, strong in orientation, fast in separation speed and high in product purity. The compound can be effectively used for preparing medicines for lowering lipids and protecting alcohol-induced liver injury, opening up new uses and medicinal values of burdock leaves, and has huge economic and social benefits. |
| priorityDate | 2021-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.