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filingDate 2021-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112933215-B
titleOfInvention Application of SIRT1 in aspect of preparing ovarian function protection medicines
abstract The invention discloses an application of SIRT1 in the aspect of preparing an ovarian function protection medicine, and belongs to the technical field of tumor fertility protection. Specifically, a gene therapy method is adopted to inject a certain dose of AdV-SIRT1 into the ovary of a tested mammal body in situ, and the overexpression level of SIRT1 is detected. The damaged part is repaired to realize the purpose of rebuilding the ovary function. Therefore, the AdV-SIRT1 recombinant vector and the pharmaceutical preparation thereof can protect the ovarian function without influencing the anti-cancer effect, and play an important role in repairing ovarian damage and/or resisting and delaying ovarian senescence and/or improving the ovarian reserve function and/or rebuilding the ovarian function and the like as novel medicines.
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