http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112924695-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01F1-0018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01F41-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01F41-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01F1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112924695-B |
titleOfInvention | Composite magnetic nanomaterials based on DNA tetrahedron, preparation and application |
abstract | The invention relates to the technical field of functionalized magnetic nanomaterials, and provides a composite magnetic nanomaterial based on DNA tetrahedron, preparation and application. Magnetic nanoparticles are loaded on the surface of molybdenum sulfide particles, gold nanoparticles are modified on the exposed active sulfur atoms of molybdenum disulfide particles, DNA tetrahedrons are modified on gold nanoparticles, and protein-linked antibodies are incubated on DNA tetrahedrons. The material prepared by the method of the present invention is used for the enrichment and detection of low-abundance proteins in serum, and can efficiently and selectively enrich specific low-abundance proteins in serum through the specific reaction between antigen-antibody , and the material is based on magnetic nanomaterials, so it has the characteristics of easy and fast use, greatly shortens the processing time of serum complex matrices, and can achieve efficient and highly selective enrichment of low-abundance proteins in complex matrices. |
priorityDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.