http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112920287-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105
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filingDate 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112920287-B
titleOfInvention Amomum villosum polysaccharide with immunoregulation effect and preparation method and application thereof
abstract The invention discloses amomum villosum polysaccharide with an immunoregulation effect and a preparation method and application thereof. The invention separates the great molecular weight acidic polysaccharide AVPG-2 of the amomum villosum for the first time, and the great molecular weight acidic polysaccharide AVPG-2 is measured by a high-efficiency size exclusion chromatography and multi-angle laser light scattering instrument combined differential detector (HPSEC-MALLS-RID), and the weight average molecular weight is 1.48 multiplied by 10 7 Da, analyzed by HPLC, the polysaccharide AVPG-2 of amomum villosum is mainly composed of rhamnose, glucuronic acid,Galacturonic acid, glucose, galactose, xylose and arabinose. According to Congo red analysis, the structure has a triple helix structure. AVPG-2 can remarkably promote macrophage RAW 264.7 to generate NO and secrete cell factors IL-6 and TNF- α And the cell activity and phagocytic capacity of macrophage RAW 264.7 are improved, and the preparation method is expected to be used for preparing immunoregulation health-care products or medicines.
priorityDate 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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