http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112920199-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112920199-B |
| titleOfInvention | A piperazinone substitute or derivative thereof, preparation method and application thereof, and pharmaceutical composition |
| abstract | A piperazinone substitute or a derivative thereof, a preparation method and application thereof, and a pharmaceutical composition belong to the technical field of antitumor drugs. This application designs a heterocyclic small molecule compound substituted with piperazinone. This compound exhibits good affinity to PI3Kδ. This compound can down-regulate the activity of PI3K pathway in tumor cells, thus exhibiting good inhibitory activity on PI3Kδ-dependent tumors. , is expected to be used as one of the components of pharmaceutical preparations for the treatment of different tumors. Moreover, the preparation method of the piperazinone substitute of the present application is simple and convenient, and the yield is high. |
| priorityDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 214.