Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b94af04e3798f8a1020f076bf65891af |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2820-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14152 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
filingDate |
2019-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07755a517c5f0799fd7016caea49f36d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9de23df2e60147ef1b06c637a1bedbbc |
publicationDate |
2021-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-112912506-A |
titleOfInvention |
Adeno-associated virus vector producing cell lines |
abstract |
The present invention relates to an adeno-associated virus (AAV) vector-producing cell comprising a nucleic acid sequence encoding: AAV rep and cap genes, helper viral genes, and the DNA genome of the AAV vector; the AAV rep gene comprises an intron comprising a transcription termination sequence having a first recombination site upstream of the transcription termination sequence and a second recombination site downstream of the transcription termination sequence; and the nucleic acid sequences are all integrated together at a single locus within the genome of the AAV vector-producing cell. The invention also relates to methods for generating AAV vector-producing cell lines. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116262934-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116376843-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116376843-B |
priorityDate |
2018-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |