| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K125-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 |
| filingDate |
2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2023-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2023-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112891361-B |
| titleOfInvention |
Application of Pubescenoside C in the preparation of drugs for the prevention and treatment of myocardial ischemia-reperfusion injury |
| abstract |
The invention provides the application of Pubescenoside C, a triterpene saponin compound of Ilex pubescens, in the preparation of medicines for preventing and treating myocardial ischemia-reperfusion injury. The triterpenoid saponin compound Pubescenoside C can mediate the polarization of macrophages from M1 type to M2 type by regulating the interaction of HSP90/GSK-3β, thereby improving myocardial ischemia-reperfusion injury and myocardial tissue lesions, reducing The role of myocardial injury. The hollywort triterpene saponin compound Pubescenoside C can also be prepared into medicines in different dosage forms in combination with other pharmaceutical excipients, and the prepared medicines can be used to prevent and treat myocardial ischemia-reperfusion injury. |
| priorityDate |
2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |