http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112891351-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 |
| filingDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112891351-B |
| titleOfInvention | Application of naphthalimide-polyamine derivative and mitoxantrone in preparation of antitumor drugs |
| abstract | The invention belongs to the technical field of medicinal chemistry, and particularly relates to application of a naphthalimide-polyamine derivative and mitoxantrone in preparation of antitumor drugs. The invention provides an application of a naphthalimide-polyamine derivative combined with mitoxantrone in preparing an antitumor drug by combining the naphthalimide-polyamine derivative with Mitoxantrone (MIT). Test results prove that the naphthalimide-polyamine derivative and mitoxantrone jointly act on human colorectal cancer cells and mouse colorectal cancer cells, show stronger colorectal cancer inhibition activity and better synergistic tumor inhibition effect, thereby having better practical application value. The combination of a naphthalimide-polyamine derivative and mitoxantrone can be a novel method of treatment for patients with colorectal cancer. |
| priorityDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.