http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112877264-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate | 2021-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112877264-B |
| titleOfInvention | Pseudomonas putida mutant strain and application thereof in biological preparation of 6-hydroxynicotinic acid |
| abstract | The invention discloses a pseudomonas putida mutant strain and application thereof in biological preparation of 6-hydroxynicotinic acid. The pseudomonas putida mutant strain is preserved in the China general microbiological culture Collection center of the culture Collection of microorganisms with the preservation date: 2021, 3/8, storage address: no. 3 of Beijing West Lu No.1 of Chaoyang district, the preservation number is CGMCC No. 21876. The mutant strain Pseudomonas putida S14 mut-5 of the invention has the activity of 2.68 U.mL ‑1 It is 2.4 times of wild type. The strain has obviously improved substrate tolerance, can be combined with nitrilase for application, and can convert 3-cyanopyridine for accumulation to obtain 54.5 g.L of 6-hydroxynicotinic acid ‑1 The optimum pH value is 6.0, and compared with most of niacin dehydrogenases which prefer neutrality and alkalinity, the method is more suitable for industrial production conditions and has wide development prospect in industrial application. |
| priorityDate | 2021-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.