http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112876570-B
Outgoing Links
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-12022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-12034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 |
filingDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112876570-B |
titleOfInvention | African swine fever virus vaccine and preparation method thereof |
abstract | The invention discloses an African swine fever vaccine and a preparation method thereof. The present invention displays African swine fever virus structural proteins P72, P30, P54 or CD2v-AC on the surface of the self-assembled ferritin cage structure respectively, improves the humoral immune efficacy and width of the vaccine, and improves the immunogen of the African swine fever virus structural protein sex. The present invention also recombines the structural proteins P30, P54 and CD2v to obtain recombinant proteins and connects them with ubiquitin to obtain two recombinant proteins, further improving the cellular immune effect of the African swine fever virus structural protein, and providing better immune protection to animals . The present invention also provides a method for preparing the recombinant protein or African swine fever vaccine. The African swine fever vaccine provided by the invention can induce broadly neutralizing anti-African swine fever antibodies, not only improves the immune efficacy but also expands the immune range, provides effective immune protection against virulent infection, and has become a universal safe vaccine with multiple protective effects potential. |
priorityDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 851.