http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112876404-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48 |
| filingDate | 2021-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112876404-B |
| titleOfInvention | A kind of synthetic method of phthalimide type trifluoromethyl sulfide reagent |
| abstract | The invention belongs to the technical field of organic compound synthesis, and relates to a method for synthesizing a class of phthalimide-type trifluoromethyl sulfide reagents. The general structural formula of this kind of reagent is as formula (1): A method for synthesizing a phthalimide-type trifluoromethyl vulcanization reagent comprises using a nitrogen halogenated compound containing a phthalimide structural skeleton as a reaction substrate, and using trifluoromethyl thioester as a trifluoro compound The source of methylthio group was used to synthesize the phthalimide-type trifluoromethyl sulfide reagent. In the present invention, trifluoromethyl thioester is used as the source of trifluoromethyl thio group, and under the activation of fluoride anion, trifluoromethyl sulfide anion is generated, and the reaction substrate is nucleophilically substituted, so as to realize the construction of nitrogen-sulfur bond, and after separation and purification The phthalimide-type trifluoromethyl sulfide reagent is obtained. The method for synthesizing the phthalimide-type trifluoromethane vulcanization reagent described in the present invention has the advantages of easy preparation of raw materials and low price of the reaction reagent, which significantly reduces the sulfidation of the phthalimide-type trifluoromethane sulfide. The synthetic cost of the reagent is beneficial to industrial production; the synthetic conditions are mild, the operation is simple and safe; no transition metal elements are required, and the method is environmentally friendly. |
| priorityDate | 2021-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.