| abstract |
The invention belongs to the field of natural macromolecular biomedical materials, and in particular relates to a whole blood perfusion adsorbent, a preparation method and application thereof, wherein the adsorbent is a natural macromolecular nanofiber and inorganic functional filler, organic functional filler and/or organic coating Material composite large-sized nanofiber porous network microspheres, wherein the inorganic functional fillers and organic functional fillers are wrapped in natural polymer nanofiber microspheres, and the organic coating material is wrapped in natural polymer nanofiber microspheres. surface of the ball. The whole blood perfusion adsorbent of the present invention has a microsphere size suitable for whole blood perfusion, has good blood compatibility, has a nanofiber porous network structure, and has inorganic and organic functional materials that specifically adsorb toxins, and can be designed for specific toxins. The corresponding whole blood perfusion adsorbent has high adsorption efficiency and strong selectivity, and is easy to popularize and apply. |