| abstract |
The invention discloses an application of brimonidine in the preparation of anesthetic drugs, and relates to the technical field of medicine. The anesthetic drug is specifically a brimonidine nanogel preparation; wherein the brimonidine nanogel preparation is composed of hyaluronic acid and gelatin is obtained by mixing with brimonidine after nano-processing, the mass ratio of described hyaluronic acid and gelatin is 5-20:15-60, and the brimonidine and hyaluronic acid and gelatin total mass are The mass ratio is 1:1-8; the gel preparation can achieve mucosal administration of brimonidine in a low-dose state by nano-processing hyaluronic acid and gelatin, and has the advantages of reducing administration concentration, prolonging anesthesia time, improving Advantages of anesthesia effect. |