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filingDate 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f74a067efd009458a101b33844e6ee
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publicationDate 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112852981-A
titleOfInvention Intestinal microbial marker of abdominal aortic aneurysm and application thereof
abstract The invention relates to an intestinal microbial marker of abdominal aortic aneurysm and application thereof. The invention determines 30 intestinal microbial markers of abdominal aortic aneurysm based on a classifier modeling evaluation and verification method of intestinal microbial abundance, wherein 25 intestinal microbial markers are up-regulated and 5 intestinal microbial markers are down-regulated, and high-risk groups of abdominal aortic aneurysm can be effectively screened or early patients can be found according to the intestinal microbial markers of abdominal aortic aneurysm, so that the abdominal aortic aneurysm can be prevented from further expanding and the rupture risk can be reduced as soon as possible, and the treatment effect of the abdominal aortic aneurysm can be monitored. Meanwhile, the intestinal microbial marker can be used for preparing a diagnostic kit and a therapeutic drug. The invention overcomes the defects that the existing abdominal aortic aneurysm diagnosis can not realize early screening and can not predict the onset and development trend of the abdominal aortic aneurysm, and the like, and can help disease pathological typing, medicine action target point research, accurate medication, pathogenesis research and the like.
priorityDate 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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