http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112852817-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate | 2021-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2023-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2023-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112852817-B |
titleOfInvention | A composition and application for RNA editing in Type III-A CRISPR-Csm system |
abstract | The invention belongs to the technical field of gene editing, in particular to a composition and application for RNA editing in a type III-A CRISPR-Csm system. The composition includes a Csm complex and a guide RNA targeting a target RNA sequence, the Csm complex is composed of Cas10, Csm2, Csm3, Csm4 and Csm5, and the nucleotide sequence is SEQ ID NO:1-SEQ IDNO: 5. The amino acid sequence is SEQ ID NO:6-SEQ ID NO:10. The composition provided by the present invention helps to achieve efficient editing of targeted target RNA, and provides an effective RNA editing technology system for genetic modification. In addition, the composition provided by the present invention can also be used to prepare drugs for antiviral treatment , has good application prospect and medical use. |
priorityDate | 2021-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 549.