abstract |
The invention discloses a CAR-T cell and a detection method, and relates to the technical field of CAR-T cells. The CAR-T cells can secrete the target antibody, and the N-terminus or C-terminus of the target antibody is fused with a detection tag. The antibodies secreted by the CAR-T cells disclosed in the present invention can be quantitatively detected, which provides a basis and guarantee for evaluating and monitoring the relationship between the amount of antibodies secreted by CAR-T and its therapeutic effect. |