http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112852635-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-188 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-02 |
filingDate | 2021-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112852635-B |
titleOfInvention | A fast-growing tacrolimus-producing strain and its application |
abstract | The invention relates to a strain of Streptomyces tsukuba with a significantly shortened growth cycle screened by a UV-ARTP mutagenesis method and its application. The bacterial strain is Streptomyces tsukubensis ZJBN2001 (Streptomyces tsukubensis ZJBN2001), which is preserved in the China Center for Type Culture Collection, the preservation date is December 10, 2020, the preservation number is CCTCC NO: M 2020883, and the preservation address is Wuhan, China, Wuhan University, zip code 430072 . The beneficial effects of the present invention are mainly reflected in: (1) the present invention obtains a strain with a significantly shortened growth cycle through the method of UV-ARTP mutagenesis; (2) the Streptomyces tsukuba ZJBN2001 obtained by mutation breeding by the method of the present invention, Compared with the original strain S1, the yield of tacrolimus is increased by 100%, and it can be used as the original strain of genetically engineered bacteria. (3) The method of the present invention can obtain a strain with a significantly shortened fermentation period, which is of great significance to industrial production. |
priorityDate | 2021-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.