| abstract |
The invention discloses a multifunctional nano-template based on aggregation-induced luminescence and a preparation method and application thereof. , DSPE‑PEG 2000 ‑SH and NaYF 4 : Yb 3+ , Er 3+ (up-conversion nanoparticles, UCNPs) were self-assembled, and KMnO 4 was used for surface oxidation to obtain MeOTTI, UCNPs@DSPE‑PEG@MnO 2 nanoparticles . The nano-template prepared by the invention is based on the I-type photodynamic photosensitizer with AIE properties, utilizes MnO 2 shell to consume endogenous glutathione to retain active oxygen, and introduces up-conversion nano-particles to increase the tissue penetration of light, thereby realizing Large depth phototherapy effect. |