http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112851786-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112851786-B |
titleOfInvention | Soluble Aβ1-42 variants, Aβ1-42 calibrators and kits |
abstract | The invention provides a soluble Aβ1-42 variant, an Aβ1-42 calibrator and a kit. The soluble Aβ1-42 variant comprises imino acid modification of one or more positions in the wild-type Aβ1-42 protein sequence. After the imino group on the imino acid dehydrates and condenses with the carboxyl group of other amino acids to form a peptide bond, there is no ‑N‑H‑structure anymore, and it cannot form a hydrogen bond with C=O on the peptide chain, thereby inhibiting the formation of β sheets , improve the stability of Aβ1‑42 protein in solution. |
priorityDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 141.