| abstract |
The invention discloses a dual-target antibacterial molecule of FtsZ and QseC and a preparation method and application thereof. The structure of the antibacterial molecule is shown in formula 1, wherein R 1 is H, F, Cl, Br or I; R 2 is CH 2 OH, CHO. The antibacterial effect of the antibacterial molecule against bacterial infection was evaluated by in vitro antibacterial activity experiments, and the results showed that the antibacterial molecule can effectively kill Gram-positive pathogenic bacteria and reduce the virulence of Gram-negative pathogenic bacteria, It can be used to prepare related drugs such as anti-bacterial infection. |