http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112813153-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2021-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112813153-B |
| titleOfInvention | A method for determining the downstream transcription factor interacting with target protein and its DNA binding sequence and its application |
| abstract | The invention discloses a method for determining downstream transcription factors interacting with a target protein and application thereof, and belongs to the field of biotechnology. The method provided by the present invention enriches the biotinylated proteins and their cross-linked DNA fragments in the protein samples derived from the target protein expression system by BioID, and then identifies and quantifies the enriched biotinylated proteins, and combines ChIP- The Seq method performs sequencing, library alignment and abundance detection on the enriched DNA fragments, and finally screens and determines the downstream transcription factors and their DNA-binding sequences that interact with the target protein. It has the advantages of wide detection range, accuracy and reliability, and provides The method can be used in scientific research and drug screening, etc. |
| priorityDate | 2021-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.