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filingDate 2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112791232-B
titleOfInvention Nanorod array-configured coating with anti-oxidation and self-oxygen generation functions on titanium-based surface and preparation method and application thereof
abstract The invention discloses a nanorod array formation coating with antioxidant and self-oxygen generation functions on a titanium-based surface, and a preparation method and application thereof. Firstly, preparing a porous titanium dioxide coating containing phosphorus and calcium on the surface layer of titanium or an alloy thereof by adopting micro-arc oxidation, then growing a hydroxyapatite nanorod-structured coating in situ by using a hydrothermal treatment method, preparing a poly-dopamine-coated hydroxyapatite nanorod array by using an oxidation auto-polymerization method, and finally obtaining the biomedical material with the oxidation resistance and the self-oxygen generation coating by using a poly-dopamine adsorption metal ion and hydrothermal method. The invention has stable process and strong controllability; the surface layer of the prepared coating has double effects of oxidation resistance and self-generated oxygen; the implant can regulate and control the poor bone microenvironment in the RA condition, promote the healing and regeneration capacity of bone tissues, and avoid the occurrence of side reactions such as implant failure caused by the poor bone microenvironment, coating spalling induced by poor membrane/base binding force, osteolysis or excessive inflammation induced by the coating spalling, and the like.
priorityDate 2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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