http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112791227-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0038 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L26-00 |
| filingDate | 2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112791227-B |
| titleOfInvention | A kind of composite tissue adhesive and its preparation method and application |
| abstract | The invention discloses a composite tissue adhesive and its preparation method and application. The composite tissue adhesive comprises a three-dimensional porous matrix composed of a composite hydrogel of methacrylic anhydride gelatin and polyacrylic acid grafted with N-hydroxysuccinimide, and an enhanced adhesion factor adsorbed on the surface of the matrix It is obtained by freeze-drying, and the adhesion enhancing factor is polydopamine. The composite tissue adhesive of the invention has a porous structure, which can absorb the liquid that wets the wound surface, and the polyacrylic acid has a negatively charged carboxylic acid group, which can accelerate the hydration and swelling effect of the tissue adhesive, and accelerate the drying speed of the tissue surface. Therefore, the composite tissue adhesive has a liquid absorption capacity of more than 500%, and the composite tissue adhesive of the present invention has two components that can bond with the amino groups on the wound tissue, and the tissue adhesion strength to the wet wound can be improved. above 180kPa. |
| priorityDate | 2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.