http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112791191-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
| filingDate | 2021-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112791191-B |
| titleOfInvention | Novel antibacterial peptide caprylic acid conjugate capable of efficiently resisting protease hydrolysis and multidrug-resistant bacteria and application thereof |
| abstract | The invention discloses a structural formula of a novel broad-spectrum MDR pathogenic bacterium-resisting antibacterial peptide caprylic acid conjugate SAMP-A4-C8. The antimicrobial peptide caprylic acid conjugate is an analogue of SAMP-A4 obtained by coupling caprylic acid at the amino terminal of the antimicrobial peptide SAMP-A4, and has the structure as follows: COOH-IRRRLLRV-NHCO- (CH) 2 ) 6 ‑CH 3 . The invention relates to a novel antimicrobial peptide caprylic acid conjugate which has broad-spectrum inhibition effect on gram-positive multidrug-resistant bacteria, candida tropicalis and novel cryptococcus, does not have hemolytic property, resists hydrolysis of trypsin, and has serum stability, acid-base stability and high-temperature stability. The antibacterial peptide caprylic acid conjugate provides a novel guide substance for clinical antibacterial drug research. |
| priorityDate | 2021-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.