Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff9a8a894ec90fe1c7e5ad02149075d3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-11 |
filingDate |
2021-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c54a1af8575cb80dea99da2d16b5cb7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_630cd125dfc024d8ab9230a1ecbf6b74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71ab1a62f3bf74140f4b6deaa09b640f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ca63391d5caf3664f6ec3249815d303 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_503bb733a1ddd9049b26ef555174e0bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34826d051140bd7a5b20bb77bea6a103 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_744409697a7c37b3fedb90ba612faad5 |
publicationDate |
2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-112791073-A |
titleOfInvention |
Application of α-Bromocinnamaldehyde in the Prevention and Treatment of Bacterial Infectious Diseases |
abstract |
The invention discloses the application of α-bromocinnamaldehyde for preventing and treating bacterial infectious diseases. α-bromocinnamaldehyde can inhibit the polymerization of FtsZ protein, interfere with the normal division of bacteria, and show broad-spectrum effects on Gram-positive bacteria and Gram-negative bacteria. Antibacterial activity. In a mouse model of intraperitoneal infection with multidrug-resistant bacteria, α-bromocinnamaldehyde can significantly improve the survival rate of infected animals, and has the characteristics of safety and low toxicity, indicating that α-bromocinnamaldehyde has good antibacterial activity and can be used as a treatment Leading drugs for bacterial infectious diseases. |
priorityDate |
2021-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |