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filingDate 2021-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c54a1af8575cb80dea99da2d16b5cb7d
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publicationDate 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112791073-A
titleOfInvention Application of α-Bromocinnamaldehyde in the Prevention and Treatment of Bacterial Infectious Diseases
abstract The invention discloses the application of α-bromocinnamaldehyde for preventing and treating bacterial infectious diseases. α-bromocinnamaldehyde can inhibit the polymerization of FtsZ protein, interfere with the normal division of bacteria, and show broad-spectrum effects on Gram-positive bacteria and Gram-negative bacteria. Antibacterial activity. In a mouse model of intraperitoneal infection with multidrug-resistant bacteria, α-bromocinnamaldehyde can significantly improve the survival rate of infected animals, and has the characteristics of safety and low toxicity, indicating that α-bromocinnamaldehyde has good antibacterial activity and can be used as a treatment Leading drugs for bacterial infectious diseases.
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