| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f600c9ee4c6540d4a82ad41cdf3eb21b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d94573ab2c57e8b193f3a22accddf9fe |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16234 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-62 |
| filingDate |
2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6cc6544714658416a456bd2810cddb1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4742e755645fb3069cee20adeabe0cd0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71cd4f9d79fb84394c5305f7270b40bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cec3cdefe256cefa06443ea9920b4d8c |
| publicationDate |
2021-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112778404-A |
| titleOfInvention |
A kind of self-assembled nanoparticle containing Epstein-Barr virus gHgL protein and its preparation method and application |
| abstract |
The invention discloses a self-assembled nanoparticle containing Epstein-Barr virus gHgL protein and a preparation method and application thereof. The self-assembled nanoparticle comprises a first polypeptide and a second polypeptide; the first polypeptide comprises a gHgL protein and a first carrier subunit, the second polypeptide comprises a second carrier subunit; the first The carrier subunit is I53-50A1, and the second carrier subunit is I53-50B.4PT1; the gHgL protein and the first carrier subunit are connected by a hinge. This self-assembled nanoparticle displays the gHgL protein of Epstein-Barr virus on the surface of the nanoparticle for the first time. Its particle size is larger than that of the antigen (gHgL), and it has a better antigen residence volume. More gHgL can stimulate B cells more strongly and induce higher antibody titers, which can be used to prevent Epstein-Barr virus infection and treat diseases caused by Epstein-Barr virus infection. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022160709-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113372440-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023077395-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114149979-A |
| priorityDate |
2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |