http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112778316-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-416 |
filingDate | 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112778316-B |
titleOfInvention | N- (indole-5-yl) bicyclic aromatic amide compound and preparation method and application thereof |
abstract | The invention belongs to the field of medicines, and relates to an N- (indole-5-yl) bicyclic aromatic amide compound, and a preparation method and application thereof. The structural general formula of the N- (indole-5-yl) bicyclic aromatic amide compound is as follows: a pharmaceutical composition comprises the N- (indole-5-yl) bicyclic aromatic amide compound, pharmaceutically acceptable salt, hydrate or solvate thereof and a pharmaceutically acceptable carrier. The N- (indole-5-yl) bicyclic aromatic amide compound or pharmaceutically acceptable salt, hydrate or solvate thereof or the pharmaceutical composition is applied to preparation of anti-hyperuricemia and anti-gout drugs. Experiments prove that the compound shows good effect in-vitro xanthine oxidase inhibition activity test. The preparation method provided by the invention is simple and feasible, has high yield and is easy for large-scale production. |
priorityDate | 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.