http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112778316-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437
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filingDate 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112778316-B
titleOfInvention N- (indole-5-yl) bicyclic aromatic amide compound and preparation method and application thereof
abstract The invention belongs to the field of medicines, and relates to an N- (indole-5-yl) bicyclic aromatic amide compound, and a preparation method and application thereof. The structural general formula of the N- (indole-5-yl) bicyclic aromatic amide compound is as follows: a pharmaceutical composition comprises the N- (indole-5-yl) bicyclic aromatic amide compound, pharmaceutically acceptable salt, hydrate or solvate thereof and a pharmaceutically acceptable carrier. The N- (indole-5-yl) bicyclic aromatic amide compound or pharmaceutically acceptable salt, hydrate or solvate thereof or the pharmaceutical composition is applied to preparation of anti-hyperuricemia and anti-gout drugs. Experiments prove that the compound shows good effect in-vitro xanthine oxidase inhibition activity test. The preparation method provided by the invention is simple and feasible, has high yield and is easy for large-scale production.
priorityDate 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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